“Wilding” of Laboratory Mouse Gut Microbiota at GSU

  • Presented by
    Michael W. Hart, DVM, MS, DACLAM
    Rex A. Howard, DVM, DACLAM

    For the past several years, one of Georgia State University’s (GSU) investigators (who studies inflammation and translational immunology) has had an ongoing study concerning the “wilding” of the laboratory mouse gut microbiota. We will discuss the mechanisms of wilding utilized, the success of the mechanism realized (shift in gut microbiota and immune phenotype), applications of the model, as well as challenges along the way.